JOIN US

Please join us for the 9th HBV Cure Workshop which will be organized by ANRS | EID on Tuesday, July 5, 2022. This year, the workshop will be organized in Lyon, France in a hybrid way. For those who can attend in person, we will be delighted to have you here.

Schedule

The program is scheduled in Central European Time (CET)

Welcome

Session 1: Clinical trials

Chairs: Hélène Fontaine & Jean-Michel Pawlotsky

Coffee Break

Session 2: Immune responses

Chairs: David Durantel & Hélène Strick-Marchand

Welcome

Session 1: Clinical trials

Chairs: Hélène Fontaine & Jean-Michel Pawlotsky

9:30 am – 9:45 am

Yazdan Yazdanpanah (Director of ANRS) & Fabien Zoulim (ANRS HBV cure Task Force)

9:45 am – 11:15 am

Clinical development of direct acting antivirals for chronic hepatitis B
MF Yuen (Hong Kong)

Clinical development of immune therapies for chronic hepatitis B
Harry Janssen (Rotterdam, Nertherland)

Emerging therapies for chronic hepatitis Delta
Marc Bourlière (Marseille, France)

Roundtable discussion: what will be the best combination strategies?

Coffee Break

Session 2: Immune responses

Chairs: David Durantel & Hélène Strick-Marchand

11:15 am – 11:30 am

11:30 am – 1:00 pm

New advances in the immunobiology of HBV infection
Matteo Iannacone (Milan, Italy)

Novel therapeutic vaccines in development
Robert Thimme (Freiburg, Germany)

Mechanisms of HBV-HDV interference
Julie Lucifora (Lyon, France)

Roundtable discussion

Lunch Break

Session 3: Virology

Chairs: Michael Kann & Patrick Soussan

1:00 pm – 2:00 pm

2:00 pm – 3:30 pm

cccDNA formation and DNA repair processes
Alexander Ploss (Princeton, USA)

Crosstalk between HBV and the 3D Genome
Christine Neuveut (Montpellier, France)

Targeting HBV cccDNA persistence by gene editing approaches
Barbara Testoni (Lyon, France)

Roundtable discussion

Coffee Break

Session 4: Assessing the liver reservoir

Chairs: Massimo Levrero & Vincent Leroy

9:30 am – 9:45 am

Yazdan Yazdanpanah (Director of ANRS) & Fabien Zoulim (ANRS HBV cure Task Force)

9:45 am – 11:15 am

Clinical development of direct acting antivirals for chronic hepatitis B
MF Yuen (Hong Kong)

Clinical development of immune therapies for chronic hepatitis B
Harry Janssen (Rotterdam, Nertherland)

Emerging therapies for chronic hepatitis Delta
Marc Bourlière (Marseille, France)

Roundtable discussion: what will be the best combination strategies?

11:15 am – 11:30 am

11:30 am – 1:00 pm

New advances in the immunobiology of HBV infection
Matteo Iannacone (Milan, Italy)

Novel therapeutic vaccines in development
Robert Thimme (Freiburg, Germany)

Mechanisms of HBV-HDV interference
Julie Lucifora (Lyon, France)

Roundtable discussion

3:30 pm – 3:45 pm

3:45 pm – 5:35 pm

cccDNA quantification for the investigation of new therapies
Lena Allweiss (Hamburg, Germany)

HBV integration and new HBV-associated drivers of hepatocarcinogenesis
Jean-Charles Nault (Paris, France)

Assessment of the intrahepatic immune responses
Adam Gehring (Toronto, Canada)

Non invasive biomarkers to monitor the cccDNA reservoir
Sofia Perez del Pulgar (Barcelona, Spain)

Roundtable discussion: fine needle aspirates or peripheral biomarkers?

Session 5: Roundtable discussion

Chairs: Harry Janssen & Sofia Perez del Pulgar

Farewell – Fabien Zoulim

Lunch Break

Session 3: Virology

Chairs: Michael Kann & Patrick Soussan

Coffee Break

Session 4: Assessing the liver reservoir

Chairs: Massimo Levrero & Vincent Leroy

5.35 pm – 5.55 pm

What are the remaining key challenges to cure HBV and HDV?

6:00 pm

1:00 pm – 2:00 pm

2:00 pm – 3:30 pm

cccDNA formation and DNA repair processes
Alexander Ploss (Princeton, USA)

Crosstalk between HBV and the 3D Genome
Christine Neuveut (Montpellier, France)

Targeting HBV cccDNA persistence by gene editing approaches
Barbara Testoni (Lyon, France)

Roundtable discussion

3:30 pm – 3:45 pm

3:45 pm – 5:35 pm

cccDNA quantification for the investigation of new therapies
Lena Allweiss (Hamburg, Germany)

HBV integration and new HBV-associated drivers of hepatocarcinogenesis
Jean-Charles Nault (Paris, France)

Assessment of the intrahepatic immune responses
Adam Gehring (Toronto, Canada)

Non invasive biomarkers to monitor the cccDNA reservoir
Sofia Perez del Pulgar (Barcelona, Spain)

Roundtable discussion: fine needle aspirates or peripheral biomarkers?

Session 5: Roundtable discussion

Chairs: Harry Janssen & Sofia Perez del Pulgar

Farewell – Fabien Zoulim

5.35 pm – 5.55 pm

What are the remaining key challenges to cure HBV and HDV?

6:00 pm

Registration

Registration is free but mandatory!

How to access the workshop?

How to get to Institut Lumière by Bus, Metro or Light Rail

Access by Public Transports

Lumière Institut is located 10 min away from Part-Dieu train station and 15 min away from Perrache train station

Access by road

- From Paris/Genève: South periferic exit Grange Blanche, follow Lyon Centre
- From Marseille: Lyon Centre Access then rive left, on Avenue Berthelot, take Monplaisir direction, Avenue des frères Lumière

Parking

- Free public parking (54 places): next to the Hangar du Premier-Film

Contact

Organization of the Workshop

Endorsed by

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